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Clinical Trial & Research Updates

Here you will find news updates, papers and links from the Clinical Trial Team in Birmingham, USA and other Researchers globally.

UK TREATWolfram Trial Update – Prof Barrett – June 2021

USA Trial and Research Updates from Dr Fumi Urano – May 2021

 

Acknowledgments also to the White Foundation for their help in referring patients to Dr Urano’s research. They were unfortunately omitted from the blog sent out in the newsletter.

Portugal – Wolfram syndrome: a Portuguese Research – May 2021

USA Psychiatric Diagnoses and Treatment in Wolfram Syndrome

UK TREATWolfram Trial – update from Prof Tim Barrett – February 2021

Estonian Research February 2021 – Liraglutide, 7,8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model.

UK TREATWolfram Trial – Adult’s update from Dr Ben Wright – February 2021

Due to continued Coronavirus pressure this year on delivery of adult Queen Elizabeth hospital medical services, we were requested to pause further recruitment to the TreatWolfram study. This was disappointing, but understandable. We remain committed to the safe delivery of this trial, and will seek to re-open recruitment again as soon as permitted to do so. People currently enrolled to the trial will continue to be supported by the trial team. Whilst some members of the trial team have been redeployed to other hospital roles during this time they will continue to respond to any trial questions raised but may take longer to do so. Their contact email is NeurologyResearchTeam@uhb.nhs.uk

USA Trial and Research Updates from Dr Fumi Urano – February 2021

Adult Trial Recruitment Webinar – 9th November 2020

Virtual Tour of I-Stem Research Labs, France – October 2020.

For those interested in research you might like to watch this short video from the I-Stem Research Centre in France.
I-Stem is the largest French laboratory for research and development dedicated to human pluripotent stem cells, of embryonic origin or obtained by reprogramming gene. https://www.istem.eu/en/

The video has subtitles for the researchers speaking in French, so apologies to those who are VI.

USA Trial Update from Dr Fumi Urano – September 2020

TREATWolframTrial Update from Prof Tim Barrett – September 2020 

Wolfram Syndrome Treatment Pipeline – Updated September 2020

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Two new red bars added.

Wolfram Syndrome Treatment Pipeline – Updated August 2020

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TREATWolfram Update from Prof Barrett – 15th June 2020

TREATWolfram Adult Recruitment Update from Dr Wright – 12th June 2020

USA update from Dr Fumi Urano – 25th April 2020

An easy read version of the medical research paper below.

USA Research Paper – Diabetes reversed in mice with genetically edited stem cells derived from patients – April 2020

TREATWolfram Trial Update – March 2020

USA Update from Dr Fumi Urano – February 2020

Zebrafish Model Update, UK Research (linked information on 2018 trials page) – February 2020

TREATWolfram Trial Update – November 2019

Liraglutide Research Paper, Estonia – November 2019

Zebrafish Model Update, UK Research – October 2019

Wolfram Syndrome Treatment Pipeline – Updated October 2019

Click on image for full view

TREATWolfram Trial Update – August 2019

TREATWolfram Trial Update – April 2019

TREATWolfram Trial update January 2019

TREATWolfram Clinical Trial Update – 26th November 2018

How do faults in the WFS1 gene lead to cell death in Wolfram syndrome? – posted Feb 2020

USA Dantrolene Trial Update from Fumi Urano – 26th September 2018

TREATWOLFRAM clinical trial update – September 2018

TREATWolfram Trial Update from Prof Tim Barrett – 15th July 2018

TREATWolfram Trial Important Update from Prof Tim Barrett – 30 April 2018

Bio Markers update – April 2018

Accelerating clinical trials in Wolfram syndrome: development of efficacy biomarkers and patient relevant outcome measures 1st teleconference meeting report Tuesday 24 April, 2018

USA Dantrolene Trial Update – Dr Fumi Urano, 26 April 2018

TREATWolfram Update from Prof Tim Barrett – 26th February 2018

Biomarkers Research – 31 January 2018
What are biomarkers and why are they important

TREATWolfram Update from Professor Barrett – 27 November 2017

TREATWolfram Update from Prof Tim Barrett – 6 August 2017

USA Dantrolene Safety Trial Update, Dr Fumi Urano – 1st August 2017

TREATWolfram Update from Prof Barrett – 15th June 2017

TREATWolfram Update from Prof Barrett – 9th May 2017

Lay Person Summary for clinical drug trial by Prof Barrett1st March 2017

Research Update Letter24th February 2017